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  • Rights: The University of Waikato
    Published 29 July 2008 Referencing Hub media
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    Hayley Reynolds (Auckland Bioengineering Institute) and Associate Professor Rod Dunbar (University of Auckland) explain the changes in moles that can be signs of melanoma1 developing.

    Transcript

    HAYLEY REYNOLDS
    Melanoma is largely caused by excessive sun exposure, so if someone has spent a lot of time in the sun and got sunburnt from the UV radiation2, that is the main contributor to developing melanoma. There are other factors that influence whether you will develop it or not. Someone with fair skin is more likely to get melanoma; somebody with a lot of moles – they would be more likely to develop it.

    DR ROD DUNBAR
    Most moles that you look at have a very even colouration and circumference – their shape is very smooth – they are usually circular or oval. If the colouration of the mole3 or the shape of it starts to change, that can be an indication that some of the cells within the mole have started to grow and started to turn cancerous, or have started to make more pigment4 or sometimes even less pigment – you can get melanomas that are paler than a mole would normally be. So a second and third sign of melanoma developing, apart from size, is changes in shape and colouration. Itching and bleeding are fourth and fifth signs of melanoma developing, so people have very very itchy moles, or a mole that has particularly started to bleed, and ulcers sometimes form as well. An ulcer is a dent, if you like, in the surface of the mole. And if you get an ulcerating mole that’s starting to bleed that can also be a sign of melanoma.

    Acknowledgements:
    Henry Cavillones
    Ed Tarwinski
    Carita Bonita
    Sunny Ripert
    David Benbennick
    Dr Roger Uren

    1. melanoma: A cancer of a particular type of skin cell, called a melanocyte. Melanocytes are responsible for skin colour. The cancer usually appears on the skin, but may affect the eye and membranes (for example, the lining of the nose, the meninges of the brain or the lining of the anus).
    2. radiation: Energy that is transmitted (radiates) from a source in the form of rays or waves or particles.
    3. mole: 1. A pigmented spot on the skin that contains a cluster of melanocytes. Also called a nevus. 2. (mol) One of the SI base units, the mole is defined as being the amount of substance that contains as many elementary entities as there are atoms in exactly 12 g of carbon-12.
    4. pigment: Any fine, insoluble, dry, solid particles used to give colour. In biology, the dye-like material produced generally in the superficial parts of animals that gives colour to skin, eyes and hair.
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      melanoma

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    2. A cancer of a particular type of skin cell, called a melanocyte. Melanocytes are responsible for skin colour. The cancer usually appears on the skin, but may affect the eye and membranes (for example, the lining of the nose, the meninges of the brain or the lining of the anus).

      pigment

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    4. Any fine, insoluble, dry, solid particles used to give colour. In biology, the dye-like material produced generally in the superficial parts of animals that gives colour to skin, eyes and hair.

      radiation

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    6. Energy that is transmitted (radiates) from a source in the form of rays or waves or particles.

      mole

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    8. 1. A pigmented spot on the skin that contains a cluster of melanocytes. Also called a nevus.

      2. (mol) One of the SI base units, the mole is defined as being the amount of substance that contains as many elementary entities as there are atoms in exactly 12 g of carbon-12.