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Muscle contraction

Current understanding of how muscles contract is based on the sliding filament model. This model applies to skeletal, smooth and cardiac muscle.

Very simply, during muscle contraction, a change in muscle length is caused by the thin filaments being pulled along the thick filaments. You can make a quick and easy model of this yourself by putting whiteboard markers or other fat pens (the thick filaments) between your fingers (the thin filaments). Now move your thin filaments along the thick filaments.

The first photograph on the right shows a contracted muscle where the thin filaments have moved along the thick filaments. The second photograph shows a relaxed muscle.

So although the length of the overlap of the thick and thin filaments (the sarcomere) changes, the lengths of the filaments themselves remain the same. The length of the sarcomere is a result of how far these filaments overlap.

Nature of Science

Theories are scientific explanations based on a large number of observations. Scientists propose explanations (theories) to explain the world. In science, these explanations are backed up by data (empirical evidence).

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The key to the sliding filament model is the structure of the myofilaments (within the myofibrils, within the muscle fibres, within the muscle). The two kinds of myofilaments, thick and thin, differ from each other in diameter and in the protein they are made from:

  • Thick myofilaments are thick in diameter and are made of several hundred molecules of a fibrous protein called myosin
  • Thin myofilaments are thin in diameter and are made of two linear polymers of a globular protein called actin wound in a spiral

Muscle tissue can be described in terms of units called sarcomeres, which are the portion of overlapping thick and thin filaments. This means that the length of a sarcomere is determined by the positions of the thick and thin filaments relative to each other.

This can be seen in these diagrams, which show the relative length and positions of two sarcomeres of relaxed muscle (top), partially contracted muscle (centre) and fully contracted muscle (bottom diagram).

What starts the contraction?

In skeletal muscle, this contraction is stimulated by electrical impulses carried by nerves. In cardiac and smooth muscles, the contractions are stimulated by internal pacemaker cells, which regularly contract without any conscious control.

Useful links

See an animation and explanation of the sliding filament model.
http://science.howstuffworks.com/life/human-biology/muscle.htm external link

In-depth information on muscle contraction.
http://study.com/academy/lesson/muscular-contraction-cross-bridge-formation.html external link